The phrase "a major function in" is correct and usable in written English.
It can be used to describe the significant role or purpose that something serves within a particular context or system.
Example: "The heart plays a major function in circulating blood throughout the body."
Alternatives: "a key role in" or "an essential part of".
Messenger RNA turnover has a major function in regulating gene expression and is responsive to developmental and environmental signals.
Besides a conventional water cycle, an exhaust gas cycle has a major function in the process.
Thus, epidermal LCs have a major function in uptake of lectin-binding antibodies under standard vaccination conditions.
Results of a number of studies indicate that the glutamate system, especially the N-methyl-d-aspartate (NMDA) receptor, has a major function in chronic alcoholism, including craving.
Protocadherins (Pcdhs) are a group of cell-cell adhesion molecules that are highly expressed in the nervous system and have a major function in dendrite development and neural circuit formation.
A subset of these cells is referred to as DCs; whether there is a genuine functional distinction between DCs and other MPS cells in terms of antigen-presenting activity has been debated elsewhere.5 Cells of the MPS may also act as powerful suppressors of T-cell activation and probably have a major function in the development of central and peripheral tolerance.
As reported for other CABs [ 2, 6, 13], a major function reported in this study was that of facilitating communication between the research team and the community.
More recently, the study of AGS3 null mice has indicated an unexpected function of AGS3 protein in metabolic and cardiovascular function [31], suggesting that a major function of AGS3 in vivo lies in cell metabolism.
Therefore, a major function of DISC1 in regulating mitochondrial distribution, ATP synthesis and calcium buffering may be disrupted in psychiatric disease.
Over the last two decades compelling evidence for a major function of sleep in neuroplasticity and neural network reorganization underlying learning and memory has evolved.
A major function of cAMP in eukaryotes is activation of cAMP-dependent protein kinase (PKA).
