The phrase "a major factor explaining" is correct and usable in written English.
You can use it when discussing the reasons or causes behind a particular phenomenon or outcome.
Example: "The study identified a major factor explaining the decline in bee populations as the loss of habitat due to urban development."
Alternatives: "a significant reason for" or "a key element that clarifies".
Mr Autor reckons that this is not yet a major factor explaining trends in American employment and wages.
Trophic ecology, however, was also a major factor explaining OC levels.
A major factor explaining the lack of benefit of the PAC may be that the data obtained are not useful in managing critically ill patients.
His conclusion was that climate change was a major factor explaining the disappearance of surface water and changes in vegetation due to increased aridity (Bar-Matthews et al. 1999; Hill 2006).
Intensification of world trade is a major factor explaining the increase in the number of exotic species introduced everywhere in the world [1].
This belief was considered as a major factor explaining why people ignore early symptoms and do not access treatment even after medical diagnosis.
This finding fits with others suggesting that cattle density is the major factor explaining infected tick density.
Therefore, statistical rebinding seems to be the major factor explaining the results observed at the pancreas for the dimer 2. The receptor binding of one BBN 6-14) unit will significantly enhance the local concentration of the other BBN 6-14) unit in the vicinity of the receptor which might facilitate further binding.
Therefore, differences in hunting practices are unlikely to be the major factor explaining why HIV strains emerged only in some countries.
Forwarding of outbreak cases by the LPHA managing the outbreak to the LPHAs responsible for the cases' counties of residence was the major factor explaining the missing of notified cases in the surveillance dataset.
Even though Tricyrtis produces septicidal capsule-type fruits throughout the whole genus, long-distance dispersal may not be the major factor explaining the geographical mode of speciation at infraspecific level.
