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Climate change seems to be a major exception to this rule.
Gore did, however, make a major exception to this rule by taking on a project to streamline the federal government — a task that Kerry told me made Gore less available to lobby his old friends in the Senate.
If such underperformance continues into the immediate future, as it has during the past several months, it could have negative implications for the broader market, as it seems RUT out-performance is consistent with market rallies (the August and September 2007 period being a major exception to this) and RUT underperformance is consistent with market weakness.
The "poverty" category is a "major exception" to the rule on personal relationships laid down in Oppenheim v Tobacco Securities Trust.
A major exception to this trend was a book written in 1890 by a descendant of Le Gris named F. White Le Grix, who makes a determined effort to defend his ancestor.
As much as we want to see the person who hurt us as an evil person -- as if they were a major exception to the rule, since we have falsely imagined a perfect world -- we need to realize that we're all an exception to the rule of perfection and expectation.
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The detailed analyses of the syntenic segment where Solanaceae, coffee tree and grapevine sequences are overlapping (as defined by the arrow on Figure 5) show complete syntenic conservation of eight genes between the coffee tree and Solanaceae (conservation of order and orientation) while two other syntenic genes have undergone an inversion, representing the only major exception to synteny.
The incomparable Grand Canyon of the Colorado River provides the major exception to what has proved to be an area easily traversed.
For a rejoinder, see Rickless (2007, 195, n. 2).) There is one major exception to this claim, however.
One major exception to this trend of mea culpas: Dick Cheney.
However, the major exception to this is the use of drugs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com