The phrase "a major etiologic factor" is correct and usable in written English.
It can be used in contexts related to medicine, epidemiology, or research when discussing the causes of a disease or condition.
Example: "Smoking is considered a major etiologic factor in the development of lung cancer."
Alternatives: "a significant causal factor" or "a primary contributing factor".
Conclusive evidence confirming that repetitive mechanical load is a major etiologic factor could not be found.
Janet Travell, the author of Myofascial Pain and Dysfunction: The Trigger Point Manual, speaking of the medical literature on frozen shoulder, says, "When so many authors agree that the cause of a disease is enigmatic, there is good reason to expect that a major etiologic factor is being overlooked". This major factor, according to Travell, is trigger points in the subscapularis muscle.
CRH is released by several cell types, including but not limited to neuronal cells, the gastrointestinal tracts, placenta, and fetal membranes; tPA is released in response to CRH and acts downstream of CRH receptor 1 (CRHR1), a necessary step for the activation of stress related response [37], a major etiologic factor associated with PTB.
Human papillomavirus (HPV) is a major etiologic factor for oropharyngeal squamous cell carcinoma (OPSCC).
Uveitis is a manifestation of complex processes and a major etiologic factor of visual loss.
The authors concluded that heritable hypofibrinolysis may be a major etiologic factor of primary ONFH.
The Gram-negative species Aggregatibacter actinomycetemcomitans is a major etiologic agent of human periodontitis.
Rotaviruses, a member of family Reoviridae, are a major etiologic agent of acute gastroenteritis in humans and animals worldwide.
Solar UVB radiation a major etiologic factor for this kind of malignancy produces DNA lesions such as cyclobutane pyrimidine dimers and 6-4 photoproducts in skin.
Cigarette smoking is believed to be the major etiologic factor in bronchogenic carcinoma.
Helicobacter pylori infection is the major etiologic factor of chronic gastritis and peptic ulcer in the general population.
