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VP28 is a major envelope protein that is implicated in cell attachment during infection [17], [19], [33].
Ratio of GP64 (d), a major envelope protein, to VP39 (f), a major nucleocapsid protein increased at 5 days p.i. (Table 4).
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Entry of the dengue virus (DENV) into a host cell is mediated by its major envelope protein, E. The crystal structure of the E protein reveals a hydrophobic pocket occupied by the detergent n-octyl-β-d-glucoside (β-OG) lying at a hinge region between domains I and II, which is important for the low-pH-triggered conformational rearrangement required for fusion.
VP28 is a major structural envelope protein of WSSV responsible for systemic infection in shrimp forming an important part of "infectome" that is found to be crucial in cell recognition, attaching and penetration into the shrimp cell (Chang et al. 2010; van Hulten et al. 2001).
Sequence analysis showed that a wild-type RVFV ZH501 preparation consisted of two major viral subpopulations, with a single nucleotide heterogeneity at nucleotide 847 of M segment (M847); one had a G residue at M847 encoding glycine in a major viral envelope Gn protein, while the other carried A residue encoding glutamic acid at the corresponding site.
Porcine reproductive and respiratory syndrome virus ORF5a protein is encoded in an alternate open reading frame upstream of the major envelope glycoprotein (GP5) in subgenomic mRNA5.
In fact, a tumor targeted murine IgE specific for either the major envelope glycoprotein (gp36) of mouse mammary tumor virus (MMTV) [ 45] or an antigenic determinant on the surface of human colon carcinoma cells [ 46] have shown anti-cancer effects in murine models.
This epitope was displayed, either by directly modifying the native major envelope protein gp64 of AcNPV, or by incorporating a second, modified version of gp64 onto the virus surface.
The mAb 13 C10 is directed against the 39 K major envelope protein of ORFV [ 38] and was a generous gift of C. McInnes and P. Nettleton (MRI, Pentlands Science Park, Penicuik, Scotland).
The major envelope GP5 gene of PRRSV was codon-pair deoptimized aided by a computer algorithm.
We detected both DNA polymerase and major envelope protein genes in 37 of 43 carps (86%).
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