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The phrase "a major engineering challenge" is correct and usable in written English.
You can use it when discussing significant difficulties or obstacles faced in engineering projects or tasks.
Example: "Developing a sustainable energy solution is a major engineering challenge that requires innovative thinking and collaboration."
Alternatives: "a significant engineering hurdle" or "a substantial engineering obstacle."
Exact(13)
Availability: The software is provided as part of the V3D-Neuron 1.0 package freely available at http://penglab.janelia.org/proj/v3d Contact: [email protected] A major engineering challenge recognized by the National Academy of Engineering is to reverse engineer a brain (Perry et al., 2008; Roysam et al., 2009).
Developing artificial lips flexible enough to play a trumpet was a major engineering challenge, according to Mr. Cho.
That's a major engineering challenge, much more so than a monochrome display.
The cost-effective utilization of wave energy is still a major engineering challenge.
The fluid-filling system was a major engineering challenge for the Borexino detector.
Management of ubiquitous nitrate contamination in drinking water sources is a major engineering challenge due to its negative impacts from eutrophication to immediate risk to human health.
Similar(46)
Embarking on a historic Mars surface sample return mission will provide the confirming signal that a space program is ready, willing, and capable to achieve the next major engineering challenge for exploration of our solar system.
"Network Rail has already been involved extensively with advance works and we have begun actively engaging with communities along the route to prepare communities for the impact of this major engineering challenge.
The major engineering challenge of materials in defence technologies is the vulnerability of based metals to structural and wears deformation in service.
As the field of adoptive transfer technology matures, the major engineering challenge is the development of automated cell culture systems, so that the approach can extend beyond specialized academic centers and become widely available.
The spacecraft in which the telescope and instruments were to be housed was another major engineering challenge.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com