Sentence examples for a major effect to from inspiring English sources

In addition, it was noted that siRNA injections into the primary tumor have a major effect to inhibit the development of distant metastasis in organs such as the lung and liver.

The study employs the gold standard measurements of insulin resistance (euglycemic insulin clamp) and β-cell function (disposition index) and demonstrates that EXE has a major effect to improve β-cell function but does not exert any significant insulin sensitizing action as determined by the M value during the insulin clamp.

We were unable to connect possible repeat births (i.e. siblings) to the same mother; however, the clustering that this induces is unlikely to have a major effect other than to increase slightly standard errors.

That jells with Harrison's redevelopment plan, where the focus of residential development is on units more likely to appeal to individuals or couples than to families with children, so as not to have a major effect on schools, according to Mr. Higgins of the redevelopment agency.

HIV infection has been proposed to have a major effect on OBI, leading to more consistent levels in symptomatic HIV as compared to asymptomatic HIV [ 27], being significantly associated with lower CD4+ cell counts [ 6].

The exclusion of radioactivity from the volume occupied by the TLD is a major effect that needs to be accounted for.

Existing buildings consume more energy than the new ones and building energy efficiency retrofit has a major effect in order to achieve sustainable building targets.

A major effect is attributed to prevention of a rapid raise in postprandial hyperglycemia, resulting in reduced oxidative stress and inflammatory response, fibrinogen concentration, macrophage adhesion to endothelium, and endothelial function.

Principals also need to be sensitive to the needs of their students which have a major effect on the extent to which teachers collaborate, the disciplinary climate and the type of student-teacher relationship.

There may be an increased chance of SGA, but this is not a major effect and is unlikely to be judged a contraindication to pregnancy.

Although disruption of WRKY3 and WRKY4 did not have a major effect on plant response to P. syringae, overexpression of WRKY4 greatly enhanced plant susceptibility to the bacterial pathogen and suppressed pathogen-induced PR1 gene expression.