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The phrase "a major effect for" is correct and usable in written English.
It can be used when discussing the significant impact or influence something has on a particular subject or situation.
Example: "The new policy had a major effect for improving employee morale and productivity."
Alternatives: "a significant impact on" or "a substantial influence for".
Exact(7)
Nothing would have such a major effect for so low a cost.
In this case, we don't think this bias has a major effect for several reasons.
The PVE estimation of 31.35% revealed a major effect for the QTL associated with plasma cortisol (LG 23).
Another important aspect is the finding that diabetes has a major effect for the risk of cardiovascular diseases in people otherwise at low risk.
Besides the interactions, there was a major effect for severity of trauma exposure displaying the building-block effect, and a main effect for attraction to violence.
Moreover, we could not identify any SNPs associated with Sel-BC or Xen-R insects having a major effect (for example, nonsense mutation) on the codified proteins when compared to the alleles in FRA insects.
Similar(53)
The instruction given (PEF technique or FVC technique) had a small effect for most patients (5.3% lower with FVC technique) but there was a major effect of >50 l/min for three of 36 patients which was reproducible on 3 different devices.
"A major effect of raising pay checks for earners at the bottom of the wage scale is that these earners are likely to spend more of their income on local goods and service than higher-income earners.
The two backcross datasets both provide support for a major effect of the X chromosome.
Thus, the detection of a major effect QTL for late blight resistance on the long arm of chromosome 9 of "Jacqueline Lee," along with the identification of a candidate SNP (solcap_snp_c1_10590) associated to this QTL, provides strong evidence for the location of genes controlling the trait.
Understanding these points will have a major effect on searching for new anti-malarial drug targets.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com