The phrase "a major drawback that" is correct and usable in written English.
It can be used when discussing a significant disadvantage or negative aspect of a situation, idea, or product.
Example: "One major drawback that consumers often mention is the high cost of maintenance."
Alternatives: "a significant disadvantage that" or "a key limitation that".
However, poor reactive power sharing has been identified as a major drawback that limits the implementation of the communicationless droop control in IMGs.
But there is a major drawback that may make all but the wealthiest think twice before buying property through a vehicle: Many buyers who use a trust or an LLC are not eligible for a capital-gains tax exclusion.
Clearly, however, that idea has a major drawback that is: the results in (S_{R,c}) might exhibit high degree of redundancy.
Imposition of boundary conditions of the transformed equations is a major drawback that has to be tackled, especially for three-dimensional problems.
This disparity is a major drawback that underscores the need for adjusting the electrification approach (which means that the communities or the local authorities have to request electrification at first place) adopted by the Ministry of Energy in rural electrification.
This disparity is a major drawback that underscores the need for adjusting the bottom-up approach (which means that the communities or the local authorities have to request electrification at first place) adopted by the Ministry of Energy in rural electrification.
Pre-labelling enables the analyst to track a molecule in a biological system, with the major drawback that the functionality of the target can be changed by the label itself.
While this non-discriminatory approach has some merit, it has the major drawback that a considerable amount of effort may be wasted in the HCW hand hygiene when it is not needed.
However, these techniques have one major drawback that they involve high capital and operational cost.
A January report by Human Rights Watch, probably published at the very moment the sale negotiations were coming to a close, highlights the major drawbacks that followed the arrival of al-Sisi at the head of the Egyptian state.
However, the tcDTL reconciliation problem suffers from two major drawbacks that limit its applicability in practice.
