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The phrase "a major doubt" is correct and usable in written English.
It can be used when expressing significant uncertainty or skepticism about a particular issue or situation.
Example: "There is a major doubt regarding the accuracy of the data presented in the report."
Alternatives: "a significant concern" or "a serious question".
Exact(60)
Mo Sissoko has a virus and is a major doubt, while Jeroen Tesselaar is also doubtful with strapping on a hand injury and is doubtful.
Alireza Jahanbakhsh, meanwhile, is a major doubt for Brighton.
Defender Bacary Sagna (foot) is a major doubt, but Laurent Koscielny (thigh) is definitely out.
PSG striker Ibrahimovic pulled up with a suspected hamstring injury and is now a major doubt for the return leg.
He was a major doubt for the forthcoming Davis Cup final against Sweden but eventually made the team.
There is now a major doubt over Boumsong's participation in Sunday's FA Cup fifth-round tie at home to Chelsea.
Paul Wellens is a major doubt for England's World Cup semi-final against New Zealand in Brisbane on Saturday.
"He'll be a major doubt for the Tottenham Hotspur game," confirmed the assistant first-team coach, Steve Holland.
The Celtic manager later updated his injury list, saying: "Lassad [Nouioui] is a major doubt, he was feeling his groin again.
The 21-year-old withdrew from Wales' squad to face England with a hamstring strain and is now a major doubt for the club's next two matches.
For Lamela, the good things have come, even if he is a major doubt for Saturday's FA Cup tie at Newport with a bruised glute.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com