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A 3D simulation of turbulent flow and coupled heat transfer between the working fluids poses a major difficulty because the range of length scales involved in heavy-duty radiators varies from few millimeters of the fin pitch and/or tube cross-section to several meters for the overall size of the radiator.
A major difficulty in the interpretation of test results is that of biological variability.
However, selecting the initial temperature for calculating accumulated temperature has been a major difficulty in bioclimatology because it may differ substantially in plants of the same species when influenced by varying environmental factors (Heide 1993; Murray et al. 1989).
It is a major difficulty to produce the 1 13 phase because of its low phase stability at elevated temperatures and low atomic diffusivity [11,12].
A major difficulty in determining the provenance of a piece is that ancient civilizations straddled modern-day borders.
A major difficulty is that the number of available measurements is usually lower than required.
A major difficulty in studying the origin of eusociality is choosing the right study system.
Nevertheless, a major difficulty with resistance genotyping is the interpretation of results.
Demonstration of the existence of presumed intermediary forms is a major difficulty in evolutionary research.
This gets around the difficulty of forming transmembrane pores, a major difficulty in the RNA world.
A major difficulty of the subspace iteration method with shift is that because of singularity problem, a shift close to an eigenvalue cannot be used, resulting in slower convergence.
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