Sentence examples for a major difference however from inspiring English sources

There's a major difference, however: while Malcolm was gifted, Brick (Atticus Shaffer) is smart but special-needs, with attention problems, social issues, and tics that include a habit of whispering a word after he's said it.

A major difference, however, concerns Turkey, with Washington a fervent supporter of Turkey's ambition to join the European Union and fretful that Mr. Sarkozy's opposition threatens to "antagonize a strategic ally".

A major difference however was the high level of C-RAF expression from the transgene which mediates rescue of cryptic c-MYC transformants from apoptosis (Figure S2A and S2B) leading to expansion of early tumor foci.

A major difference, however, is that 2F can be represented in more than one way.

A major difference, however, was observed between the proximal (36.2 cM) and distal (23.4 cM) regions.

A major difference, however, occurs for the MM-pair G·G, which is the least stable in our study.

The major difference, however, is that Thrun and co-founders are roboticists, and the majority of Udacity's classes are currently CS-focused, like "Building A Search Engine and Programming A Robotic Car," for example.

There is one major difference, however.

There was one major difference, however.

The major difference, however, lies in John's overall purpose.

One major difference, however, is that water scooters endanger swimmers, not grizzlies.