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The phrase "a major deviation from" is correct and usable in written English.
It can be used to describe a significant difference or departure from a standard, norm, or expectation.
Example: "The new policy represents a major deviation from our previous practices, which has raised concerns among the staff."
Alternatives: "a significant departure from" or "a substantial divergence from".
Exact(11)
This is a major deviation from the traditional ship maintenance scheme, which involves dry docking every 5 years or so, for overhaul maintenance.
"We are introducing these two concepts as a major deviation from the principle of licensing," he explained.
Some theorize that Germany's Rhine Valley will be producing luscious reds in just 50 years, a major deviation from the crisp white Rieslings that thrived for centuries in the area's cold season.
In a taped interview that aired Wednesday, Trump suggested that immigrants without documentation could pay back taxes, indicating he could be considering a pathway to legal status, which would be a major deviation from the hard line he touts.
However, we find one peculiar clade with 100% support that included 11 individuals from 8 species, a major deviation from the expected associations.
A major deviation from Models (1) and (2) is the presence of functionally differentiated alleles at different loci in a FGU.
Similar(47)
Not that he has made any major deviation from the standard US policy towards Israel, he hasn't.
All randomised patients who completed the entire treatment period without any major deviation from the protocol procedures were included in the per protocol (PP) population.
The admission that there may be some mental states (as Freud has shown) that are not within the sight of our "mental eye" as such, is a mere variation, rather than a major deviation, Ryle points out, from the basic framework of the Official Doctrine.
Nor would it require a sudden, major deviation from the standards of free speech most of the developed world respects.
Since the OFR method relies on average sequence length of a dataset, major deviation from the average length caused by indels may impact the overall species recovery.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com