The phrase "a major deviation" is correct and usable in written English.
It can be used to describe a significant departure from a standard, norm, or expected outcome in various contexts, such as research, project management, or quality control.
Example: "The results of the experiment showed a major deviation from the expected outcomes, prompting further investigation."
Alternatives: "a significant divergence" or "a substantial departure".
This was a major deviation from what Hollywood does at these events.
It's unlikely a single ship getting stuck in ice will cause a major deviation in researchers' findings.
The dot product is used as the intrinsic measure of a major deviation.
In a major deviation from Shakespear's script, Sher iff Lear (Welles) has a change of heart and joins his sons to fight hypocrisy after another Mississippi sheriff gouges out his eyes on the mistaken as sumption that he is either Peter Hoffman.
As Donald Trump continues to wrestle with how he would treat the millions of immigrants illegally living in the United States, he has made a series of comments indicating that he might be okay with some of them staying, which would be a major deviation from his earlier stance of wanting mass deportations.
At particle volumetric concentration lower than 0.36 in low-viscosity fluids, experimental particle settling velocities fall into the calculated boundaries, with a major deviation at higher fluid viscosity.
Moreover, the statistical power was sufficient to exclude any major deviation with a high probability.
(5) Per protocol (PP) set: all FAS patients without any major deviation and with a treatment duration of at least 24±2 months.
Back in 1895, when the northern clubs broke away, to take the train from Hull (the most easterly) to Widnes (the most westerly) would have taken in 21 of 22, with only (I think) Stockport having presented any major deviation.
Not that he has made any major deviation from the standard US policy towards Israel, he hasn't.
This will allow identification of any major deviation (>15 ml/kg/day) from the LWH guidelines.
