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The phrase "a major deficit of" is correct and usable in written English.
It can be used when discussing a significant lack or shortfall in a particular area, such as resources, skills, or knowledge.
Example: "The organization is facing a major deficit of funding, which is hindering its ability to operate effectively."
Alternatives: "a significant lack of" or "a substantial shortfall in".
Exact(6)
"When you have a major deficit of this size, people can jockey for position," said Arthur J. Kremer, a retired Democratic lawmaker who once led the Assembly's Ways and Means Committee.
If the bike share operates smoothly this summer, I'm predicting a major deficit of bike availability between shows during fashion week in September.
However, a major deficit of SAA1 α homozygotes was found among Karabakhian patients (4%) as compared to Armenian patients (24%) (p = 5.10−5).
Genes subject to this type of selection generally display a major deficit of non-synonymous mutations.
Residues with the lowest dfi show the highest enrichment of disease-associated variants (ratio = 1.45), whereas those with the highest dynamic flexibility show a major deficit of these variants (ratio = 0.65).
The lack of objective research methodologies is a major deficit of the studies evaluating patients with spinal stenosis, and potentially, issues of mental overlay could render the results bias.
Similar(54)
This case study in Latin Switzerland shows that a restrictive policy limiting foreign immigration of trainees would result in a major deficit in the number of anaesthetists available to meet population needs.
For instance, it was proposed that patients with schizophrenia show a major deficit in the recognition of negative emotions, but a preserved recognition of positive emotions (3).
This case study of anaesthesia care in Switzerland shows that insufficient provision of locally trained medical graduates combined to a policy limiting entry of foreign trainees is likely to cause a major deficit in the number of anaesthetists available to meet population needs.
A major deficit was the lack of a well validated questionnaire to identify sleep disorders in this population.
Dr. Krupp had treated children and teenagers with M.S. before, but each time a new patient came in, she grappled again with what she considered a major deficit in the diagnosis and treatment of the disease.
More suggestions(16)
a large deficit of
a tremendous deficit of
a great deficit of
a fundamental deficit of
a substantial deficit of
a major point of
a major component of
a major source of
a major cluster of
a major body of
a major benefactor of
a major supplier of
a major aspect of
a major tragedy of
a major target of
a major proponent of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com