The phrase "a major defect that" is correct and usable in written English.
It can be used when discussing a significant flaw or issue in a product, process, or system that requires attention or resolution.
Example: "The report highlighted a major defect that could compromise the safety of the entire structure."
Alternatives: "a significant flaw that" or "a critical issue that".
Dislocation is one of the major defects that significantly affect the photovoltaic performance.
The major defects that appear in CT image acquisition process are Beam Hardening (BH), image noise and radiation dose.
The adopted configuration drives to the achievement of coatings without solidification cracking, one of the major defects that can occur during the solidification of metallic alloys.
In Al-air batteries, the self-corrosion of Al electrodes and the parasitic hydrogen evolution during battery discharge are the major defects that lead to the degradation in the performance of the battery.
Substitution of Cu+ by Zn2 + to form ZnCu1 + donor and occupation of Cu+ at the B site of Cu2BIBII S,Se 4 to form CuB2 − acceptor are major defects that explain the relation between composition and electrical property, which are important material properties to evaluate CZTSe and CZTSSe films to be used as absorbers for solar cells.
In contrast to the major defects that may underlie chronic pseudoobstruction, even more subtle changes to the physiology of the ENS may contribute to irritable bowel syndrome and other "functional" motility disorders.
Thirty-one hips had such an extensive reconstruction of major defects that several weeks of bed rest were maintained ranging from 1 to 6 weeks.
The political life has a major defect, despite the fact that it consists in fully exercising the ethical virtues, because it is a life devoid of philosophical understanding and activity.
The report concluded that SLE is characterized by a major defect in DC homeostasis, and that IFN-α is likely to be the main cytokine contributing to this defect.
Bridges that receive a score of '4' or less on any of the three main components are deemed structurally deficient, meaning that a major defect has been found in the bridge's major support structure or deck.
