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The phrase "a major decline" is correct and usable in written English.
It can be used to describe a significant decrease in quantity, quality, or value in various contexts, such as economics, health, or performance.
Example: "The company reported a major decline in sales over the last quarter, prompting concerns about its future viability."
Alternatives: "a significant drop" or "a substantial decrease."
Exact(57)
And across North America, we did stay away, causing a major decline in air travel.
A major decline in timber harvest followed, extending an earlier downward trend.
By the middle of the 20th century, freak shows had suffered a major decline in popularity.
Although he does not expect a major decline, he does not see reasons to buy now, either.
Privately, league officials are bracing for a major decline in the cap in the 2010-11 season.
That floor is a result of a major decline in hedging by gold producers over the last two years.
The party subsequently suffered a major decline in support, falling from 54 seats in 1997 to only 31 in 2002.
He is also nostalgic about the quality of canned tuna, a product that he says he feels is on a major decline.
But if protected areas are left intact, the loss falls to 32% – a major decline, nevertheless, which would still class the species as vulnerable to extinction.
Ford said it had an inventory of vehicles that would last about 48 days — a major decline from the 80-day supply it reported earlier this year.
Possible explanations included an increase in precipitation from pre- to post-treatment, a major cone crop in 2002, and a major decline in gray fox (Urocyon cinereoargenteus) occurrence.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com