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The phrase "a major core" is correct and usable in written English.
It can be used to refer to a significant or central component of a system, idea, or organization.
Example: "The research team identified a major core of the problem that needed to be addressed before moving forward."
Alternatives: "a key component" or "a central element."
Exact(11)
A major core of Kubo-Ando theory is the one-to-one correspondence between connections and operator monotone functions.
In both designs, the graphite acts as the moderator, fuel matrix, and a major core structural component.
I was fortunate, because I had this very tight collaboration between the Rockefeller University, Columbia University, and Vassar, which was bounded by a major NIH Obesity Research Center grant, and Vassar ran a major core.
Consultation time may play a major core role in patients with psychological problems or comorbidities.
MSM have become a major core population of the HIV/AIDS epidemic in China.
Depending on its relative expression levels, this PG might be a major core protein presenting CS-GAGs on an aggressive subset of tumor cells, interacting with P-selectin.
Similar(48)
The first publically acknowledged NPP-related accident took place at Three Mile Island (TMI), 26 years after the Shippingport NPP came on line, when the plant encountered a major core-damage accident.
Only two major core topologies emerge as robust solutions: a negative feedback loop with a buffering node and an incoherent feedforward loop with a proportioner node.
The fold is stabilized by a major hydrophobic core at the junction of the two α-helices.
In some cases (I2 and I29), this reduction was also accompanied by a reduction in a major PSII core subunit, D2, suggesting that PSII was reduced overall in these cells.
The genome is surrounded by an oval core, composed of at least two major core proteins, the gene products of A3L and A10L.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com