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The phrase "a major concern and" is correct and usable in written English.
It can be used when discussing significant issues or worries, often leading into further explanation or elaboration.
Example: "The rising cost of living is a major concern and requires immediate attention from policymakers."
Alternatives: "a significant issue and" or "a pressing matter and".
Exact(60)
"That's a major concern, and it needs to end," he said in an interview.
Seven services met safeguarding standards, one had a major concern and eight had moderate concerns.
Poverty, furthermore, persisted as a major concern, and gradualism remained key to Fabian strategy.
"The players' health and safety is a major concern, and it has to be.
"It's a major concern and a frustration as well," said Hughton.
Short filter lifespan (<24h) is a major concern and could result of a procoagulating state.
That's a major concern, and it should have been dealt with at the time the work was funded," said Farrar.
For Mr. Rodriguez, this is a major concern, and further reason to minimize all of his bets.
Donor safety has always been a major concern, and potential risk to the donor must be balanced against recipient benefit.
Safe design of flood spillways is a major concern, and requires to cope with low frequency flood hazard.
Paul D. Tonko, president of the authority, said that the technical problems had not been a major concern and that he was satisfied with Verdant's progress.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com