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The phrase "a major complication" is correct and usable in written English.
It can be used when discussing significant issues or challenges that arise in a situation, particularly in medical, technical, or project contexts.
Example: "The surgery went well, but there was a major complication that required immediate attention from the medical team."
Alternatives: "a significant issue" or "a serious problem."
Exact(60)
A major complication is Manhattan's lack of a traditional multiple listing service.
A major complication for those seeking housing for the elderly is the licensing and standards issue.
With brain surgery, the possibility of a major complication can't be excluded.
Pancreatitis is a major complication of ERCP.
Diabetic ketoacidosis (DKA) is a major complication of diabetes mellitus.
Radiocontrast nephropathy (RCN) is a major complication after radiographic examination.
Acetabular osteolysis is a major complication of total hip arthroplasty.
Gastric ulcer is a major complication of gastrointestinal disease.
Postoperative peritoneal adhesions are a major complication of abdominal surgery.
Bracket loss is a major complication in lingual orthodontic treatment.
This is a major complication for regression methods which all depend on mean CPU utilization measurements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com