The phrase "a major complement of" is correct and usable in written English.
It can be used to describe something that significantly enhances or completes another thing, often in contexts related to components or elements of a whole.
Example: "The new software update is a major complement of our existing system, improving its overall functionality."
Alternatives: "a key component of" or "an essential part of".
We show here that CR4, a major complement receptor on macrophages and MGCs, is not required for the phagocytosis of complement-opsonized targets.
Reporting that tens of thousands of Iraqi troops were moving south across Iraq toward Kuwait, Pentagon officials said today that it will take about a month to place the first major complement of American ground forces in Saudi Arabia.
Vascular EC represented a cell type on which to test this hypothesis, because the endothelium is exposed to hypoxia, as evidenced by expression of HIF-1α [ 6], and represents a major site of complement deposition in the rheumatoid joint [ 9].
This review focuses on the classic complement pathway and the role of major complement inhibitory factors in cancer immune evasion as well as on how current protein engineering efforts are being employed to increase complement fixing or to reverse complement resistance leading to better therapeutic outcomes in oncology.
Expression levels of major complement factors, complement regulators, and apoptosis factors in septic encephalopathy model were evaluated by real-time PCR.
Although most clinical laboratories measure overall complement activity (CH50) as well as the levels of major complement proteins such as C3 and C4, these are not terribly helpful in most situations in which complement activation occurs because these complement proteins are acute phase reactants.
C1 is the multimolecular protease that triggers activation of the classical pathway of complement, a major element of antimicrobial host defense also involved in immune tolerance and various pathologies.
In survival experiments using C3 deficient mice, we did not find a major role of the complement system for the survival after post-exposure immunization (Fig. 5C).
There is strong evidence from human immunohistochemical, genetic and proteomic studies supporting a major role of the complement system in AMD pathogenesis, and this is further supported by a large number of in vitro and animal studies.
Alterations in functional activities of classical, alternative and lectin pathways of complement, a major mediator of the immune response, as well as changes in blood levels and expression profiles of its C1q, C3, and C4 components have been detected in schizophrenia-affected subjects [ 18- 22].
Clair's description of his professional role neatly complemented a major theme of his most famous client's defense.
