Sentence examples for a major clinical problem from inspiring English sources

Critical limb ischemia is a major clinical problem.

Marginal integrity is a major clinical problem in restorative dentistry.

Resistance to adjuvant systemic treatment, including taxanes (docetaxel and paclitaxel) is a major clinical problem for breast cancer patients.

Study objective: Acute rejection (AR) of the allograft is a major clinical problem after lungtransplantation.

Theoretical Biology & Medical Modelling 4: 4. Background: Tissue invasion, one of the hallmarks of cancer, is a major clinical problem.

Recognizing that skeletal metastases are a major clinical problem with PCa, further assessment of this paradigm was pursued with an established PCa bone metastasis model13.

Cytomegalovirus infection in renal transplant recipients is a major clinical problem, with both short and long term sequelae.

Local tumor recurrence remains a major clinical problem following surgical treatment for most cancers such as hepatocellular carcinoma (HCC).

Obesity complicating pregnancy continues to be a major clinical problem for the obstetrician and the obstetric anaesthetist.

Type-B reactions, therefore, represent a major clinical problem [7].

Management of infection is a major clinical problem.