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The phrase "a major case for" is correct and usable in written English.
It can be used when discussing a significant argument or justification for a particular position or action.
Example: "The research presents a major case for the need to invest in renewable energy sources."
Alternatives: "a strong argument for" or "a compelling reason for".
Exact(1)
Hadid's scraped-back hair at the OnePiece New York Concept Store Grand Opening makes a major case for using hair gel again.
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Swoboda, joined by his wife, Cecilia, and their two grown sons, came in from New Orleans, admitting to a major case of nostalgia for Shea, not so much for the seats and the girders and the ramps, but for the name itself.
It's jam-packed with cuteness, so prepare yourself for a major case of "the feels"!
On Monday, a major case about corporate accountability for extreme violations of human rights, Kiobel v. Royal Dutch Petroleum, is scheduled to be reargued.
After suffering a courtroom defeat in a major case, it is not unusual for a defendant to bring in additional expertise for the appeals, according to legal experts.
While he waited for a major case with which to test his discovery, he was scooped in 1846 by a Boston dentist, William Thomas Green Morton, the most controversial figure in Fenster's narrative.
It was also the first major case for a young county prosecutor, not far removed from law school and just months into the job, who said he was confident that the case would be solved soon.
In this study, we investigated how the primary longitudinal flow would affect vortex formations in the cells by designing three different MCR models and simulating three major cases for each model.
It often took a major court case for them to prove their worth.
Medical diagnosing and treatment have already proven to be a major use case for virtual reality.
Temporal reasoning has always been a major test case for knowledge representation formalisms.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com