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'a major bottleneck' is a correct and very common phrase in written English
You can use it when referring to a situation or obstacle that is preventing forward progress or progress from being made. For example: "The lack of resources is proving to be a major bottleneck for the project's completion."
Exact(60)
It's this last step that's currently a major bottleneck.
Especially with automatic sampling, data evaluation becomes a major bottleneck.
Within the PSP problem loop refinement is a major bottleneck.
For Windows users, viruses can also be a major bottleneck for online connections.
Currently, a major bottleneck in metagenomics is the reconstruction of genomes from closely related strains.
Controlling DNA repair is still a major bottleneck in developing gene editing for clinical applications.
The station now is a major bottleneck that causes serious delays.
New Jersey commuter trains share a 100-year-old tunnel with Amtrak, a major bottleneck.
But a major bottleneck ahead of him on the road to stardom saw him choose a different route altogether.
That would eliminate the lag time in retrieving data from the hard disk, a major bottleneck in current computers.
Part supply is a major bottleneck for successful automation in micro assembly.
More suggestions(18)
a substantial bottleneck
a major obstruction
a major gridlock
a great bottleneck
a large bottleneck
a serious bottleneck
a major hindrance
a major pitfall
a major roadblock
a primary bottleneck
a major hurdle
a major barrier
a major constraint
a major blockage
a major problem
a major impediment
a fundamental bottleneck
a severe bottleneck
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com