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The phrase "a major base" is correct and usable in written English.
It can be used to refer to a significant or primary location, foundation, or support for something, such as a military operation, business, or concept.
Example: "The company established a major base in the region to enhance its operations and reach new markets."
Alternatives: "a key foundation" or "a primary hub".
Exact(58)
Russia has roughly 20,000 troops and a major base in Tajikistan, on the Afghan border.
A major base of the Argentine Air Force is located there.
By destroying white farms, Mr. Mugabe wiped out a major base of black opposition.
Lying on the eastern outskirts of Grozny, Khankala is a major base for the Russian assault on Grozny.
About a third of the way down lie the ruins of Tulum, once a major base of Mayan civilisation.
In the following months Hollandia was converted into a major base and command post for the Southwest Pacific area.
Its location is also critical: it abuts the Mezze military airport, a major base for Syrian forces.
Occupied by the Germans in World War I, it became a major base for the Ypres front.
As dawn broke over Tianjin, which is a major base for China's petrochemical and shipping industries, the extent of the destruction became clear.
He said that group, which is supported by Iran, uses the villages of the south as a major base of operations, which deeply concerns Israel.
Those are among the most well-guarded spots in Kandahar, the biggest city in southern Afghanistan and a major base for NATO forces.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com