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"Smoking in films remains a major and persistent driver of smoking uptake among children and young people, which the actions of irresponsible film makers, incompetent regulators and insouciant politicians are abjectly failing to control," wrote Alison Lyons and John Britton from the centre.
Neurological injury after cardiac surgery, particularly after hypothermic circulatory arrest (HCA), remains a major and persistent problem.
Despite international progress in scaling up HIV prevention and treatment efforts, negative attitudes and discriminatory practices towards persons living with HIV/AIDS (PLWH) represent a major and persistent barrier [ 1- 17].
This result is of special interest since in BALB-neuT mice anti-neu vaccination affords a major and persistent protection against incipient mammary tumors whereas it is no longer able to extend the survival time of mice if started when mice display multiple invasive microscopic carcinomas (week 16) [ 22].
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This became another major and persistent concern, although meta-analytic evidence does not support a higher incidence of such outcomes [ 5].
The inhibitory effect of bacteriophage against lactic acid starters is still recognized as one of the major and persistent troubles in dairy fermentations.
Other major and persistent risk factors were externalizing problems and male gender.
Major and persistent infectious disease threats, their global incidence, and some of the global health commitments made to address them are shown in the Technical Appendix.
Food intake of five pesticides, namely, chlorpyrifos, permethrin, endosulfan, dieldrin and 1,1-dichloro-2,2-bis p-chlorophenyl 1,1-dichloro-2,2-bis p-chlorophenyl 1,1-dichloro-2,2-bis p-chlorophenyl 1,1-dichloro-2,2-bis p-chlorophenyl 1,1-dichloro-2,2-bis p-chlorophenylethyleneach fooDDEthe [ 29].
The HRH situation was described in April 2004 by the MoH as "dangerously close to collapse" and as a "major, persistent and deepening crisis" [ 23].
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting and persistent consequence of numerous classes of antineoplastic agents, affecting up to 30%40%% of patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com