Sentence examples for a major activation of from inspiring English sources

This activity was not due to a decline in the numbers or functional capacity of CD4+CD25+Foxp3+ Tregs but rather to a major activation of 'diabetogenic' T cells.

Nevertheless, it is of interest that both studies showed a major activation of non-olfactory regions, suggesting that components of human sweat may affect the human brain in an odor-unrelated manner.

Thus, our data do not point to a major activation of HoCC upon starvation, unless the autophagy machinery is disrupted.

A major activation of zygotic transcription occurs together with degradation of maternal mRNAs during the midblastula transition in several vertebrate systems.

A major activation of ERK 1/2 was also observed from 10 to 15 minutes after TGF-β1 challenge, whereas a strong phosphorylation of Smad 3 was noted at 30 and 60 minutes.

In addition, Liu et al. [ 122] demonstrated in a mouse model that stroke induced a major activation of AMPK in young animals but no response occurred in their older counterparts.

A second major activation, associated with the perception of chemosensory anxiety signals, is located in the precuneus.

In addition, the overrepresented GO terms reflected the regulation of a major developmental shift: activation of MAPKK activity, negative regulation of ethylene-mediated signaling pathway, and transmembrane receptor protein serine/threonine kinase signaling pathway (Table  2).

As GSK3 has a major role in activation of p53, as well as in activation of MITF and USF1, in response to inhibition of PI 3-kinase, we further investigated the role of GSK3 in apoptosis both in wild-type Rat-1 cells and in cells expressing dominant-negative p53.

Angiotensinogen is the principal substrate of renin, and a major driver of activation of the renin-angiotensin system (RAS).

A major effect of activation of transcription factors of the NF κB family is the transcriptional upregulation of survival genes.