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The phrase "a main question raised" is correct and usable in written English.
It can be used when discussing a significant or central question that has been brought up in a conversation, text, or analysis.
Example: "In the discussion about climate change, a main question raised was how to effectively reduce carbon emissions."
Alternatives: "a key question posed" or "a primary question raised".
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Whether the resulting scale-free dynamics exhibited by both cellular systems stems from scale-free networks is a main question raised by our findings.
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A positive answer could therefore be given to the main question raised by the Minister: based on the current evidence available, it is considered safe to play sports on STP with the rubber infill in place in the Netherlands.
But the main question raised is clear enough: why is Unocal before an American court for actions it did not take, and which were done neither in America nor to an American?In this section Is Big Blue the Next Big Thing?
The main question raised by these studies is whether GABA itself serves as a signaling molecule in plants.
The main question raised about the measure, though, is whether it can be enforced consistently by police officers who usually have more pressing matters to deal with.
The main question raised by our data is the biological significance of this miRNA response.
The detection of average and/or variance changes is dealt as a classical change-point problem analysis where the two main questions raised are: 1) "Did a change really occur?" and 2) "When did it occur?".
Here's a look at some of the main questions raised about Benghazi and what investigations have concluded.
At the last COST (European Cooperation in Science and Technology) EU US meeting held in May 2011 in Prague, one of the main questions raised was how can molecular chemistry with an emphasis on the use of non noble metal complexes contribute to water photolysis for the production of solar fuels.
One of the main questions raised by the Fed's action was whether it had waited too long.
Through interviews with central actors in the planning process and analyses of planning documents on municipal and county level, the main questions raised are how municipal planners relate to questions concerning integration of historic fabric in new urban development.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com