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Discover LudwigThe phrase "a main established" is not correct in English and does not convey a clear meaning.
It seems to be an incomplete or improperly structured phrase, and it is unclear when it could be used without additional context.
Example: "The organization has a main established protocol for handling emergencies."
Alternatives: "a primary established" or "a key established".
Exact(1)
Smoking, a main established cause of small cell and non-small cell lung cancer, contributes to 80%and90%0% of lung cancer deaths in women and men (U.S. Department of Health and Human Services 2004).
Similar(59)
Thus, carrying the MBL-high genotype seems to double the risk of RF-negative RA in never smokers, namely a subgroup in which the main established genetic risk factors (SE and the PTPN22*620W allele) do not play a significant role.
The main established Christian groups are Roman Catholics, Methodists, Anglicans, and Baptists.
Of all the main established major players, Northcliffe was always best placed to lead in such a venture for one simple reason – lack of debt.
The various parts of this system (BACs, CHAPS etc) are largely owned by the main established UK banks and effectively self regulated.
Although the main established mechanisms for clearance of calcium phosphates are phagocytosis and acidification [32], the RES is also capable of eliminating them [33].
The main established pathway for insulin-stimulated GLUT4 translocation involves the activation of the insulin receptor and the two downstream kinases PI3K and Akt.
The main established independent prognostic factors for RCC are TNM stage, tumour size, nodal status and histological grade (Ficarra et al, 2008; Lam et al, 2008).
The initial plan had been to establish a main base and two satellite bases – spread out so they could take a good range of geographical and meteorological observations – further along the coast.
In both novels a main character establishes a new religion.
Deregulated proliferation underlies the entire spectrum of precancerous breast lesions and it is also a main feature of established cancer [ 22].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com