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The phrase "a main challenge that" is correct and usable in written English.
You can use it when discussing significant difficulties or obstacles in a particular context or situation.
Example: "A main challenge that we face in this project is the limited budget available for resources."
Alternatives: "a primary obstacle that" or "a key difficulty that".
Exact(3)
A main challenge that currently hinders the implementation of this promising process is the risk of polymerisation of acrylic acid and n-butyl acrylate.
A main challenge that engineers face is, thus, how to design and install the pipeline and transmission system to assure that the multiphase fluids will be safely and economically transported from well locations all the way to the downstream processing plants.
The importance of MHL in help-seeking behaviour has also been studied, with evidence indicating that lack of MHL is a main challenge that patients and families face in seeking help, 13 14 especially in Asian cultures, where utilisation of mental health services is lower across the board.
Similar(57)
However, compared to the traditional SCs, the relatively poor PCE for this kind of HHSC is still the main challenge that prevent them from becoming a competitive PV technology.
The main challenge that comes up with increasing of this integration is uncertain generation of these resources, which affects the networks parameters and optimization strategies.
Taking into account these results, it is evident that in order to develop cIO-based LICs the improvement of the cycle life of these LICs is presently the main challenge that needs to be overcome.
The main challenge that faces decision makers is to stop the degradation of the natural resource of water while materializing the national vision that demands "Sustainable development and management of the Kingdom's water resources" (MOWE 2012).
The main challenge that has been treated within the paper is the technical feasibility of the hydrogen supply chain, that is mainly driven by uncertain, but clean solar and wind energy resources.
The main challenge that I face on a daily basis is the high level of unscheduled call outs.
Considering all these issues, the main challenge that arises is the setting up of a wireless network where the legitimate members of a group will be able to establish a protected wireless network.
So what has been the main challenge that you have met in terms of cross-cultural management? A. Hierarchy is always a bit of an issue.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com