The phrase "a main assumption of" is correct and usable in written English.
It can be used when discussing a fundamental belief or premise that underlies a particular argument, theory, or study.
Example: "A main assumption of this research is that all participants will respond honestly to the survey questions."
Alternatives: "a key premise of" or "a primary belief of".
Thus, a main assumption within this school of thought is that fashionable management ideas primarily lead to temporary discourse within organisations, which often remains decoupled from action [ 43– 43].
We demonstrate here that the amount of nonspecific binding exhibited by MM oligos is dependent upon the individual nucleotide substitutions they incorporate, and therefore not necessarily equivalent to that experienced by the PM probe – this finding undercuts a main assumption underlying the use of MM probes.
Nonetheless, while MR may be a useful tool to examine POE, its underlying main assumption of a strong association between the utilized genetic variants and the examined disorder is challenging to meet for ADHD, as, to date, no genome-wide association was reported for this condition.
While the line transect method assumes that the probability of detecting objects on the line (distance=0) is p=1, and as objects are far from the line the probability of detection follows a certain declining function, the main assumption of the strip transect method is that the probability of detecting objects within the strip is 1 (i.e. no objects are left undetected).
The main assumption of this method is that there is a time interval preceding the outcome being studied, in this case death from lung cancer, when individuals would be too sick and/or ineligible to enroll in a study.
The main assumption of our work is that roles respond to a division of labor that reflects different functions, or behavior, within the network.
The main assumption of NSA is that gains of both chromosomes in a tumor sample are very unlikely to occur.
In addition, the decision for a cell to undergo apoptosis may be determined in prior generations, contradicting the main assumption of the model.
The main assumption of WGCNA is that genes with similar expression patterns in a number of individuals are interconnected.
Main assumption of both models is that vehicle paths through roundabouts consist of few connected radii.
