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He wanted "to set in motion a machinery which will bring noblest ideas to the doorstep of even the poorest and the meanest".
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Viral RNA caps can be synthesized or acquired through the use of a capping machinery which exhibits a significant diversity in organization, structure and mechanism relative to that of their cellular host.
The genome sequence of L. plantarum 80 harboured genes encoding a respiration machinery, which is an energetically favourable metabolic pathway that leads to less oxidative and acid stress in LAB [ 68].
Heidegger seems to mean us to take his words seriously: Aesthetic representation now possesses "a conceptual machinery which nothing can stand against".
Finally, these 20 22 nucleotides are incorporated into a composite machinery, which promotes partial duplex formation between the short RNA and the 3' untranslated regions (UTR) of targeted mRNAs, resulting typically in mammals in translational silencing [6], [7].
Their 3′-end processing is conducted by a different machinery, which will be the focus of this section.
Calcium transients are important events for cell physiology and the regulation of this signaling process depends on a complex machinery, which maintains cytosolic calcium at nanomolar levels in resting conditions [ 23].
Saccharomyces cerevisiae has an NMD machinery which is, however, not essential.
In fact, results generated by several studies indicate that most experimental approaches that interfere with the development of morphine analgesic tolerance can be assembled into a common regulatory machinery, which connects MOR and NMDAR function [37].
The microsatellite instability (MSI) pathway characterizes about 15% of the colorectal cancers and is associated with diploid or near-diploid tumors and a defective MMR machinery, which is reflected as MSI in the tumor tissue.
However, coupling of the transmembrane proton gradient to synthetic reactions – even in most primitive bacteria – is performed by a sophisticated enzyme machinery which seems to be evolutionarily recent [ 73].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com