In 22 years Soll, the University of Iowa's Carver/Emil Witschi Professor of Biological Sciences, has transformed DSHB into a vast, nonprofit resource for animal cell researchers using hybridomas (hybrid cells bred by fusing an antibody-producing lymphocyte with a tumor cell).
In order to substantiate the idea of a defined T cell mechanical behavior associated with activation triggering, we brought into contact a primary CD4+ lymphocyte with a simplified model of an APC by using an adapted version of the BFP.
KHYG-1 natural killer T (NK/T) cells established from a patient with aggressive NK/T cell lymphoma displayed morphology of a large granular lymphocyte with a large nucleus, rough chromatin, and bulk basophilic cytoplasm.
Co-culture of autologous lymphocytes with DC-Ad-CALR or DC-Ad-CM significantly increased the numbers of induced CD8+ CTLs.
Perforin expression denotes a T lymphocyte with cytotoxic potential.
The genetic manipulation of donor lymphocytes with a suicide gene is a promising strategy to increase feasibility and safety of allo-HCT.
In addition, splenic and hepatic T lymphocytes were rapidly activated as demonstrated by the expression of CD69+ on CD4+ lymphocytes with a time dependent manner (Fig. 1D).
Macrophage was the most numerous kind of cell in pericoronitis, but CD2+ T lymphocytes, with a normal CD4/CD8 ratio, were also increased (P <.01).
To establish an in vitro system that mimics the infection state in an epithelium, we co-culture lymphocytes with a widely used epithelial cell line, Madin-Darby canine kidney (MDCK) cells.
Adult T-cell leukemia/lymphoma (ATL) is a malignancy of peripheral T-lymphocytes with a poor prognosis.
