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According to the same logic, this could have biased our set of BRCA1 carriers towards those with a lower than average density.
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The energy density fluctuations should, when inflation ends, correspond to regions of average, greater-than-average, or lower-than-average density, depending on how the fluctuations work.
As a result, these four chromosome regions also showed a lower-than-average marker density in the consensus map.
It is known that gene density is positively correlated with G+C content [ 2] and that the heterochromatic regions surrounding centromeres and telomeres have a lower than average gene density [ 3- 5].
The result is that high-scoring regions are reduced by a negligible amount, whereas regions of lower than average density are reduced to nearly zero all in a continuous manner (e.g. ρref≈0.541, and s≈0.110 for D.melanogaster using the Tinman motif).
It commanded a lower-than-average sales premium.
Many such problems, including environmental monitoring, involve large deployment scenarios with lower-than-average node density, as well as a long time scale and limited budgets.
The average population density in the sub-region, 18 ishabitants/km2, is lower than the average density of the Middle East region as a whole, which is 43 inhabitants/km2.
This risk could be related to personal and family characteristics or to lower-than-average bone-mineral density.
Data indicate that children without obvious metabolic bone diseases who experience their first fractures early in life are especially vulnerable to further fractures [ 3, 12], perhaps owing to lower-than-average bone-mineral density [ 13- 17].
Given the complexity of variable regions and the difficulty to genotype within and around them, it is worth noting that the average number of SNPs that could be analyzed (1/2059 bp) was slightly lower than the average density in HapMap (1/1495 bp; according to the total number of polymorphic common-to-all-population SNPs) [28].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com