Exact(1)
Nowadays vaccines contain highly hydrolyzed porcine gelatin, which shows a lower sensitization rate with a subsequent decrease of vaccines allergic reactions [55].
Similar(59)
Additionally, several models have shown paradoxical dose response relationships, such that a lower skin sensitization dose can result in greater lung inflammation upon inhalation challenge than a higher sensitization dose, and that isocyanate-specific antibody responses may not correlate with asthmatic responses (Herrick et al. 2002; Vanoirbeek et al. 2004).
Lower efficiency of shRNA mediated TAK1 knockdown in HuH7 cells may explain this lower sensitization to TRAIL.
Meanwhile, Spanish patients showed a lower percentage of sensitization towards Ara h 8 (only 2% versus 35% in our study population) and Bet v 1 (6.5% versus 37% among our patients).
This would suggest that the higher prevalence of CBD in our study population was not solely related to the long latency since last exposure because we would have expected a lower rate of sensitization alone without CBD if increased prevalence of CBD was solely caused by the long latency.
Our cohort presented a lower prevalence of HLA-sensitization, probably due to its low immunological risk character and an earlier done antibody screening.
Lower MELs for MI in rinse-off products indicate a lower likelihood to induce skin sensitization, also after multiple daily applications.
However, animals pretreated with 3 high doses (24-h apart) of amphetamine (14 mg/kg IP) or apomorphine (40 mg/kg SC) did demonstrate sensitization to a lower test dose of amphetamine (7 mg/kg IP) or apomorphine (3 mg/kg SC) when placed in an environment that was different from the pretreatment environment.
However, animals pretreated with three high doses (24 h apart) of amphetamine (14 mg/kg, IP) or apomorphine (40 mg/kg, SC) did demonstrate sensitization to a lower test dose of amphetamine (7 mg/kg, IP) or apomorphine (3 mg/kg, SC) when placed in an environment that was different from the pretreatment environment.
Thus, a reduced immune response to beryllium may account for the association of beryllium sensitization with a lower body burden of insoluble beryllium or predominantly soluble beryllium exposure compared with individuals with CBD.
Although Leynaert et al. [ 41] found adults who had lived on a farm as a child had lower levels of cat sensitization and a lower risk of nasal symptoms in the presence of pollen, they found no consistent association between living on a farm in childhood and the risk of asthma or wheeze: a similar proportion had 'atopic asthma' in the farm and non-farm groups.
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