The phrase "a low linkage of" is not commonly used in written English and may sound awkward or unclear.
It could be used in contexts discussing relationships or connections that are weak or minimal, but clarity may be an issue.
Example: "The study revealed a low linkage of social factors to the overall health outcomes of the participants."
Alternatives: "a weak connection of" or "a minimal association of".
Some studies conducted in Uganda [ 11] and other African countries [ 12– 14] have reported a low linkage to HIV care of newly diagnosed HIV sero-positive individuals.
For example, records that match perfectly or nearly perfectly on first name, surname, date of birth, and address have a high linkage weight, and records that match only on date of birth have a low linkage weight.
29 Relatively low linkage rates of 26-41% among residents of shelters, rooming houses, and hotels presumably reflect the fact that many such individuals would not have filed a tax return or remained for long at the same address.
A few individual SNPs were assigned to linkage groups based on slightly lower LOD scores (LOD > 55) together with comparative association, whereas the remaining small linkage groups and singletons were rejected as a consequence of low linkage ability.
The formation of ISR in H. pylori increases allelic diversity, and contributes to the uniquely low linkage disequilibrium characteristic of this pathogen.
The approach differs from QTL mapping in that it uses large outbred populations with low linkage disequilibrium instead of family pedigrees (Neale and Savolainen 2004; Gonzalez-Martinez et al. 2006).
The authors attributed the association of the "flipped" allele (G instead of A) to (i) a high minor allele frequency of rs760317, (ii) an unidentified additional causal SNP of relatively low linkage disequilibrium with rs760317, and (iii) no consideration of the interaction between the two in their analysis model.
First, the selected SNPs and VNTRs might not have covered all genetic variation within the dopaminergic genes examined, specifically in the case of low linkage disequilibrium between variants within a gene.
The accuracy of genomic prediction with Bayesian models is lower in populations with a large effective population size and thus a low amount of linkage disequilibrium [ 4].
Similarly, isolates of C. gloeosporioides from strawberry revealed a low level of linkage disequilibrium as would be expected in sexually recombining populations (Ureña-Padilla et al. 2002).
