Sentence examples for a low brain from inspiring English sources

Our model drug Rhodamine 123 (Rh123) exhibits, like domperidone, a low brain permeability since both substances are recognized by efflux transporters at the BBB.

30 Although a high level of serum leptin is a poor anorectic, a low brain level of leptin is a powerful orexigen.

A number of studies to date support the concept of diminished brain iron in RLS/WED, thus providing the basis for the hypothesis that RLS/WED occurs as a result of low brain iron content [ 8- 10].

This in silico approach led to the discovery of LBP1, an orally bioavailable, low brain penetrant CB1 receptor agonist with robust activity in rodent models of neuropathic pain and a good preclinical therapeutic profile, which was selected for clinical development.

Stegosaurus had a relatively low brain-to-body mass ratio.

However, since peptides are generally poor candidates for therapeutic agents due to their poor metabolic stability and low brain bioavailability, a search for alternative strategies for the development of galanin-based anti-convulsant drugs was prompted.

Mark Farren has been playing with a low grade brain tumour since being diagnosed last year.

The theory goes that an imbalance in serotonin levels – caused by low brain cell production of serotonin – equates to depression.

This, in turn, attributes a positive effect to insulin administration even at low brain glucose of 5 mM or less despite significantly increased brain glutamate concentrations.

In a biodistribution experiment using normal mice, these probes showed low brain uptake (0.33% and 0.36% ID/g) at 2 min post-injection.

Brain hypoxia (low brain tissue oxygen tension, PbtO2) is an independent predictor of poor outcome, regardless of intracranial pressure (ICP), cerebral perfusion pressure (CPP) and injury severity [ 6].