Sentence examples for a loss of sequence from inspiring English sources

This will lead to a loss of sequence and associated expression value per gene.

One way to show that a loss of sequence detectability is a loss-of-function is to show that the loss is by deletion of sequence, because a deleted sequence cannot function.

Solanaceae and Poaceae do not share a common ancestor to the exclusion of the other well-represented families [ 21], so this pattern must require either independent increases in CEP sequence diversity in the Solanaceae and Poaceae lineages, or a loss of sequence diversity in the rosid clade which includes the other well-represented angiosperm plant families.

The absence of TIR sequences in the grasses has to be inferred as a loss of this sequence type from the grasses because TIR homologs have been found in pine [ 31] and moss [ 59].

All of these precepts may contribute to a loss of substantial sequence information.

In the absence of telomerase, canonical DNA polymerases cannot maintain telomere length, resulting in a loss of telomere sequence with each cell division.

For instance, a submicroscopic 258 Kb deletion, detected 11,320 bp upstream of DAX1 in a 21-year-old 46,XY female, may lead to a loss of regulatory sequences and position-effect upregulation of DAX1 expression [36].

Using this system we determined the chemical requirements of the process and demonstrated that eccDNA is formed by excision from the chromosome, thereby leading to a loss of genomic sequences.

As described by Slijepcevic [ 92], the mechanism of Rb translocations can be either 1) associated with a loss of telomeric sequences prior to fusion or 2) with their preservation in otherwise inactivated telomeres.

More than 50% of the tumours with a loss of 17q sequences had an amplification of c-erbB-2 which is located on 17q12-21, indicathat that only one of the chromosomes may be involved in the amplification of the c-erbB-2.

Conversely, 303 (2.4%) of the gg2v3 models do not have matches on the v4 assembly, which indicates a loss of some sequences in v4 compared to v3. 82.5% of the gg2v4 models (N = 9,184) map completely to a unique locus in v3 and likely represent loci that are shared between the v3 and v4 genome assemblies.