Sentence examples for a loop switch from inspiring English sources

α4 contacts both PP2Ac surface residues and inner structures that are exposed upon unfolding of a helix and a loop switch near the active site.

A weak loop switch effect of 0.01-0.004 mV was also observed when switching the fluidic loop, this was probably caused by minute changes of pH or salinity in the sample buffer resting in the sample coil.

A loop-flipping event is counted if a given loop switches from a cytoplasmic to periplasmic (or vice versa) position according to the definitions in the main text and if the y-position of the reference bead in the loop (defined in the main text) is at least 4.5 σ after the flip (to exclude counting the rapid flipping of loops within the translocon channel).

On ADP release or ATP binding, a subunit loop switches position from the bottom to the top of the staircase, grabbing the 3′ nt immediately ahead of the protein and only releasing the nucleotide six catalytic steps (i.e. one complete catalytic cycle) later; this requires a ∼15 Å movement of the loop.

Specifically, we demonstrated that the backbone torsion-angles of residues in the catalytic loop switch from a "relaxed" to "strained" conformation upon kinase activation and the strained geometry results in a network of hydrogen bonds involving conserved non-catalytic residues in the ATP and substrate binding lobes.

The effect immediately disappeared after one loop switch and was avoided using a continuous buffer flow.

It has a converter domain, and a P-loop, switch I and switch II near the active site.

Lines beneath the alignment show the locations of the P loop, Switch I-II and the GTP binding loop motifs (G1-5).

There was significantly more flexibility in the de novo mutant simulations (T99M, R216C, E253K), particularly at the nucleotide-binding loop, switch II, and β5 regions.

Reduction of the disulfide bond leads to a large structural change where the catalytic loop switches to an open conformation permitting access to the substrate and cofactor binding sites (r.m.s.d. 4.1 Å over 11 residues of the catalytic loop).

Loop switching could be a mechanism for control of gene expression.