Sentence examples for a longer target from inspiring English sources
Observed ATS were also longer when SPC charts were designed with a longer target ATS and change in EDE was small.
Hou et al. reported that a Cas9 protein from Neisseria meningitides could recognize a longer target sequence than the one from S. pyogenes, which consequently improved the target specificity of the CRISPR/Cas system.
Although higher conservation among CTCF-binding events, relative to tissue-specific TFs, could be due solely to the information content or length of the bound motif, we found that conservation of CTCF-binding events across mammalian genomes is not purely the result of a longer target motif.
Here we devise a scanning variant of LocARNA, called LocARNAscan, that computes alignments of a query RNA with a much longer target sequence based on sequence and structure similarity.
There were multiple sets of primers used for the analysis of the multicopy IS6110 target region: one PCR which used IS6110 primers [32] for a slightly longer target of 246 bp; another set of primers [33] that amplify a 123 bp product and a third set used in conjunction with the former for a nested PCR [20] which give a 92 bp product.
The largest difference between our AnkB/AS structure and the reported ANKRA2/HDAC4 and RFXANK/RFX5 structures is that AnkB uses a much longer target binding groove than the other two ankyrin repeats in binding to its targets.
Based on these insights, we developed TTK inhibitors, based on a (5,6-dihydro pyrimido[4,5-e]indolizine 5,6-dihydro pyrimido[4,5-e]indolizine 5,6-dihydro pyrimido[4,5-e]indolizinescaffoldocket surrounding Lys553.
We think this has been exacerbated by concerns around the production outlook, which is to achieve an exit rate of 75,000 barrels a day this year, with a longer term target of 100,000 barrels by 2015.
For detection rates, the interaction effect essentially reflects a longer lasting target detection advantage for the shift than for the no-shift cue (p = 0.016 on the 800 ms CTOA, [shift detection rate] – [no-shift detection rate] = 9%, light box on figure 3B).
The theoretical objective was to elucidate the effect of the complex structure of a longer RNA target molecule on hybridization kinetics.
There are longer target times in residential areas and the countryside.
