The phrase "a locus with a" is correct and usable in written English.
It can be used in contexts related to mathematics, science, or discussions about locations or points of interest.
Example: "In geometry, a locus with a specific set of points can help define the shape of a figure."
Alternatives: "a point with a" or "a location with a".
Further evidence implicating epidermal barrier function in asthma pathogenesis came recently from a large genome-wide study showing that a locus with a likely function in keratinocytes (RORA) was among ten loci most strongly associated with this disease [19].
Region IL21/IL21-AS1 an an example of a locus with a prioritized cell type.
Therefore, the demographic history of a locus with a high density of SNPs will be overrepresented in the overall inference.
SNP rs4977574 is located at a locus with a gene encoding a large antisense noncoding RNA (ANRIL) [ 21, 22].
We postulate a locus with a minimum of two DIP-genes, possibly including one or two enhancers or cis-regulatory elements,, on the basis of these results.
Genotypes in Hardy Weinberg equilibrium were generated at a locus with a MAF of 0.5 and explaining 1.5 and 1 % variance in the phenotype.
Efficient HR-mediated insertional mutagenesis was also achieved at the endogenous PIG-A locus, with a > 200-fold enhancement by ZFNs targeted to that gene.
By applying a CT value of 0.9 to the maximum probability of all possible pairs of HLA alleles, the highest accuracy was increased to 99.09% at the HLA-C locus (with a call rate of 82.40%, from Illumina 550 K), and the lowest accuracy was increased to 91.58% at the HLA-A locus (with a call rate of 41.65%, from Affy 5.0).
Ten evenly spaced markers on each of the three chromosomes that did not contain a locus with an effect on the trait were selected and all 4525 possible models using these 30 markers were fitted.
A locus with an observed state frequency above the confidence interval is labeled as significantly distorted.
Similar to A-FABP deficiency in experimental models, a genetic variant at A-FABP locus with reduction in A-FABP expression reduced the risk for cardiovascular disease and type 2 diabetes in a population genetic study [10].
