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The phrase "a localized duplication of" is correct and usable in written English.
It can be used in contexts related to biology, genetics, or any field discussing the replication of structures or elements in a specific area.
Example: "The study revealed a localized duplication of genes within the chromosome, which may contribute to the observed phenotypic variations."
Alternatives: "a specific replication of" or "a regional copy of".
Exact(1)
We found evidence for a localized duplication of the SWS2 opsins in O. latipes and O. niloticus, since both these species have two adjacent SWS2 opsin genes (Additional file 4).
Similar(59)
In the case of polyploidy, the population dynamic and stoichiometric effects are different from the case of a localized duplication in a diploid background.
However, the Type IIa-2 and IIb subfamilies are consistently found on the same chromosome, flanked by some syntenic genes, indicative of a localized segmental duplication [ 13, 15].
Dismissing the phone-hacking scandal as a localized outbreak of criminality, he questioned the very need for a public inquiry.
Resistivity dipoles result from a current flowing around a localized region of increased resistance23,24.
None of the physicians could explain what would cause a localized outbreak of an autoimmune condition.
This may eventually cause a localized thinning of it.
For each AR, a localized group of SRs were found.
Disseminated porokeratosis is a localized alteration of keratinization.
In spite of a large number of governing equations, the model has a quite simple mathematical structure: it is a duplication of a single visco-elastic model.
Afterward there was a duplication of the ceremony and a banquet for 350 people.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com