The phrase "a local and systematic" is correct and usable in written English.
It can be used in contexts where you are describing something that is both specific to a particular area and organized in a methodical way.
Example: "The research focused on a local and systematic approach to addressing community health issues."
Alternatives: "a regional and organized" or "a specific and methodical".
Interestingly, the level of miRnov_10 was repressed in leaves on day 14 and induced in roots at 6 h, which might indicate that miRnov_10 plays an important role in local and systematic P signaling pathways.
Another interesting finding of our study was the fact that RDW was positively associated with the Fuhrman grade in clear cell carcinoma in the general trend; this particular finding was in accordance with the rationale of elevation of RDW according to the presence of a more active inflammatory process, as a higher tumor grade generally enhances the local and systematic inflammatory reaction [ 33].
However, their use may put patients at risk of local and systematic infectious complications, including both localized site infections and central line-associated bloodstream infections (CLABSI).
Thus, the engraftment of MSCs had a protective effect on smoke inhalation injury through regulation of the local and systematic VEGF and reduction of lung water content.
For example, tissue injury can cause endothelial injuries associated with local and systematic inflammatory reactions; these reactions are important for the production of tissue factor and factor VII, which can excessively activate coagulation.
● Reduce mean levels of local and systematic inflammatory mediators.
This complication was managed by daily wound changes and the use of local and systematic antibiotics.
In addition, in the stroma, TGFβ promotes local and systematic immune suppression, thereby allowing transformed cells to escape immune surveillance, further promoting tumor metastasis [ 19, 21, 22].
In this regard, SCs secretory factors have been shown to exert therapeutic effects by the modulation of local and systematic inflammatory responses, the stimulation of local tissue regeneration, and/or recruitment of host cells.
