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The WPMN agreed on a priority list of nanomaterials and a list of endpoints relevant for environmental safety testing.
In 2007, the WPMN launched the Sponsorship Programme on the Testing on Manufactured Nanomaterials and agreed on a priority list of nanomaterials and a list of endpoints relevant for environmental safety testing.
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An interim analysis will be performed when half of the patients are recruited, blinded to investigators in order to a) detect possible imbalances between the three arms of the trial with respect to a list of independent secondary endpoints, and b) assess whether the primary efficacy endpoint was obtained at this point in the trial.
The main objective of this study was to draw up a list of potential surrogate endpoints for OS in digestive oncology trials, by way of a survey among clinicians and methodologists involved in the conduct of clinical trials.
The intersection staircase will be represented by a list of the right upper endpoints with decreasing y-coordinates and increasing x-coordinates.
The EU list of endpoints for each a.s.s
The EU list of endpoints provided for some a.s.s
With some rare exceptions, the toxicity data compiled from the EU list of endpoints represent for each a.s. the most sensitive species within a taxonomic group, i.e., the lowest toxicity measure for each of the six here investigated endpoints as selected by the EU review procedure from all available validated data.
The algorithm to solve problem 2 is then: (9) OPT 2 (j ) = max { OPT 2 (j − 1 ), OPT 2 (c (j ) ) + p (a j, b j, Γ ) } where OPT2 j) is the optimal non-overlapping set of domains for the jth domain in a list of domains sorted by their endpoints (OPT2(0)=0), and c(j) is the closest domain before j that does not overlap with j.
The second data set was collected from the so-called "list of endpoints" of the EU authorization procedure for pesticide a.s.s
The second data set ("most sensitive endpoints") was derived from the list of endpoints identified during the European review process for new and existing a.s.s
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