The phrase "a linear pathway of" is correct and usable in written English.
It can be used to describe a straightforward or direct route or process, often in contexts related to development, progress, or movement.
Example: "The research outlined a linear pathway of development for the new technology, ensuring each phase was clearly defined."
Alternatives: "a direct route of" or "a straightforward course of".
Uveal melanoma (UM) is characterized by mutually exclusive activating mutations in GNAQ, GNA11, CYSLTR2, and PLCB4, four genes in a linear pathway to activation of PLCβ in almost all tumors and loss of BAP1 in the aggressive subset.
Thus, taken together, the phenotypic and molecular data suggest this cluster of genes functions as a linear pathway to regulate progress of Yor1 out of the ER and through the Golgi for delivery to the plasma membrane.
The absence of fadB and fadJ in E. coli LSBJ in combination with the plasmid-borne recombinant enzymes PhaC1 STQK) and PhaJ4 establishes a linear pathway for the production of PHA polymers from free fatty acids.
These data are consistent with our previous genetic and biochemical studies of the HMT-1-dependent heavy metal detoxification pathway [8], [16] and show that hmt-1 and pcs-1 do not act in a linear pathway for the detoxification of other heavy metals as well as Cd.
Results from examining ABA-responsive root elongation phenotypes of these ethylene auxin double mutants are consistent with auxin and ethylene acting in a linear pathway to affect ABA-responsive inhibition of primary root elongation.
Because double mutants between ein2 and auxin-resistant mutants do not display additive phenotypes, auxin and ethylene likely act in a linear pathway to affect ABA-responsive inhibition of primary root elongation.
A linear pathway consists of a series of steps in a relatively strict order.
If molecules function in a linear pathway, ectopic activation of the upstream component might allow genetic dissection of pathway colinearity.
Moreover, these features were shown to be linked in a linear pathway: low-levels of cysteine protease activity triggered mitochondrial dysregulation, which preceded the amplification of cysteine protease activity and ultimately led to DNA fragmentation and the parasite's death.
Gab2 may also act in a linear pathway upstream or downstream of signal transducer and activator of transcription-5 (STaT5), a major positive regulator of HSC function.
