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Results: The injections were well tolerated and the specimens displayed a limited regression of the lesions.
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We limited regression analyses for the full cohort (5,752 workers) to exploring exposure metrics and birth cohort effects.
In autism, there may be a limited period of regression.
Recognizing the complex correlation structure among the PCB congeners (Additional file 1: Table S1) and with a limited sample size, standard regression strategies are problematic (e.g., [ 10]).
Often, these models are either derived using linear regression on a limited set of experimenter-selected metrics, or using more complex algorithms such as neural networks.
TSCM can induce effective tumor regression when a limited number of cells are used.
Although this study refers to a decent sample size, a limitation is the low number of events (n=21), which may explain why PSA was not a predictor of failure in the cohort of localised PCA cases in this setting and which results in a limited degree of freedom in regression models.
Proportional hazards modeling was conducted in a similar manner to the logistic regression modeling, using a limited backwards selection procedure.
As multivariate logistic regression can handle a limited number of covariates simultaneously [ 9], it might therefore be poorly adapted to large epidemiologic datasets for identifying independent associations.
The basis function method (BFM) [ 24] is a much faster and less noise-sensitive method, as it linearizes the model equation and solves it for each voxel using standard linear regression applied to a limited number of predefined possible values of MBF.
Although our funnel meta-regression analysis showed a limited publication bias (Additional file 1: Fig. S2), the bias was always difficult to ascertain with a small sample number of the included studies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com