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Alignment of the putative VP1 amino acid sequences of HEV strains with their respective prototype strains revealed a limited divergence; only 2 substitutions were found in CVA21, and 9 substitutions and 1 deletion was found in EV68 (data not shown).
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Their limited divergence suggests a very recent origin for these taxa or mitochondrial exchange during the Pleistocene.
When the density fit scores are equal, the new conformation is chosen, since it is more likely a rotameric conformation, given the limited divergence radius of the refinement.
Strikingly, this strain was found to represent a very similar hybrid to MCO456, with regions of homozygosity and heterozygosity showing a high level of overlap and limited divergence at the sequence level between AY2 and MCO456 (99.997% identity at the nucleotide level).
Low complexity is consistent with relatively recent proliferation of a small number of originating TE's resulting in limited divergence of k-mers.
Additionally, the recent discovery of incomplete dosage compensation in a fish with XY sex determination may be due to limited divergence between the nascent sex chromosomes (Leder et al. 2010).
In contrast, directional selection yielded tightly clustered evolved morphologies distant from the origin of principal component plots with limited divergence from the selection trend and monotonic rise in divergence from starting morphology over time (Polly 2004:Fig. 7).
The zone of bony fixation is narrow and the pins are biomechanically compromised being under significant cantilever loading due to limited divergence in cancellous bone and significant loading from the force of distraction and the weight of the leg below the hip joint.
Similarly, M. arosiense, despite having extremely limited divergence with MIP on comparison of its marker genes used in this study, is a pathogenic scotochromogen that grows optimally at 42°C and takes more than 14 days for visible colonies to appear on 7H11 agar, that too with a heavy inoculum [12].
In our study, host species jump by C. abortus may be indicated by C. psittaci 84/2334, which grouped close to all C. abortus strains, showing limited divergence with C. abortus with only 7 fixed nucleotide substitutions and should therefore be classified as C. abortus.
Modest sequence differences within and outside PARCEL domains reveal only limited divergence.
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