Furthermore, short-read sequences may be unreliable for polymorphism screening due to a high likelihood of incorrect assignment when a pseudogene or retrogene is highly similar to its parent gene, as NANOGP8 is to NANOG.
If there was any doubt as to whether or not a study could be excluded, a full text screen was performed to reduce the likelihood of incorrect exclusion of a relevant study.
For PNs and care chain partners alike, this double data entry took longer, increased the likelihood of incorrect and incomplete data and led to staff dissatisfaction.
This restriction was made in order to reduce the likelihood of incorrect assignments by the BLASTN procedure (see Additional file 4: Table S3, cluster BLASTN assignation sheet).
This resulted in numerous hypotheses being tested but most p-values were very low or very high, reducing the likelihood of incorrect inferences.
VQSR can be combined with separate filters used to flag for additional investigation genomic regions with increased likelihood of missed/artifactual variants or genotypes with increased likelihood of incorrect zygosity.
In the meantime, physicians are encouraged to explore not only the possibility that PPI treatment is not optimized (even if they believe it to be) but also the likelihood of incorrect diagnosis and/or the potential benefits of adjunctive therapies.
"So it has a likelihood of lasting much longer".
The sequence-based algorithm builds up plausible sequences of individual journey segments and is a good fit for validation of other algorithms, as it has a lower likelihood of assigning incorrect identities and illustrates all possible options rather than only the best match.
Large observational studies confounded by severity of illness have a high likelihood of obtaining incorrect results even after employing conventionally "acceptable" levels of risk-adjustment, with large effect sizes that may be construed as true associations.
