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A library comprising 44 diversely substituted aurones derivatives was synthesized by straightforward aldol condensation reactions of benzofuranones and the appropriately substituted benzaldehydes.
As a part of the screening initiative, a library comprising more than 10,000 chemicals was screened in high-throughput assays against a panel of 12 different biological targets involved in two major groups of biochemical pathways: the nuclear receptor pathway and the stress response pathway.
A library comprising 6144 DArT clones was constructed using the approach described in Figure 1 (see Methods for details).
The tool refers to a library comprising 1,325 mutations that is the most comprehensive and accurate such data source yet reported.
To elucidate potential signaling pathways and adhesion molecules that influence mesoderm migration, we conducted a screen of a library comprising 311 insertions at the presumed 5′ end of genes encoding cell surface or secreted (CSS) factors.
Using this protocol, we constructed a library comprising more than 6,000 DArT clones, of which at least 5.70% were highly reliable polymorphic markers for two closely related mosquito strains separated by only a few generations of artificial selection.
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To this end, developers can use the framework's provisioning support, which contains the APIs, provided by the provisioning agent, and a provisioning library comprising a number of functions that facilitate provisioning of the software-defined gateways.
To delineate various repetitive elements present in the C. floridanus genome, RepeatMasker v 4.0 [ 102] was applied using a custom library comprising a combination of Repbase library [ 32] and the de novo repeat library customised for the C. floridanus genome constructed with RepeatModeler [ 103] with default parameters.
It includes three resources that assist the user to robustly predict in silico fragmentation patterns: a set of general fragmentation rules, a fragmentation library comprising ∼150 000 fragmentation mechanisms collected from the scientific literature and user-specified mechanisms.
A combinatorial library comprising 64 ligands based on the Ugi reaction was prepared and screened for binding GFP-tagged and non-tagged proteins.
For this purpose, the three PDZ domains were first screened for binding with a peptide library comprising 6223 human C termini created by SPOT synthesis.
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