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At a level of single proteins, we see quite some divergence between the results of EVfold-PLM and PconsFold in Figure 5.
We demonstrated that the transition between OR and AND gates is accomplished by the change of a level of single component (either decrease of pro-apoptotic protein Bad or increase of pro-survival Bcl-xL), without any modification of topology of the network or even kinetic rate parameters.
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As noted by the authors, targeting GSK3 is a more specific and limited approach than targeting PI3K/AKT, though from a tumor biology perspective inhibition of AKT may result in a greater level of single agent tumor cell killing.
The ITS2 sequences from members of the Anopheles gambiae complex (ITS2 ~ 426 nt) reveal a low level of single nucleotide polymorphisms between cryptic species [ 16, 29].
Apart from an unusually high transition bias, another signature of gene conversion associated mutation is a high level of single nucleotide deletions relative to base pair substitutions [ 13], and so here I also examine deletions within CDEII.
An alternative is the use of a specialized DSP that is optimized for a high level of single-instruction, multiple-data (SIMD) parallelism.
Sequencing depth distribution showed that ∼94% of the assemblies had greater than 20-fold coverage, ensuring a high level of single-base accuracy (Supplementary information, Figure S1B).
Behind this new style of photography is the idea that the moving wand of a scanner can capture a sense of perspective, a richness of color and a level of detail that a single, static lens cannot.
His own research has even shown a placebo response at the level of single brain cells in patients suffering from Parkinson's disease.
We built a multiple alignment at the level of single repeats to define the EPTP repeat consensus sequence (Figure 5).
This is not an average result, but a result that holds on the level of single runs and at the level of IEI.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com